Biclonal B-Chronic Lymphocytic Leukemia: A rare Case Report with Review of Literature
Bansal Shashi, Syeda Firdos Jamil, Talwar Amandeep, Sharma Upendra
Asian Hematology Research Journal · pp. 35–39 · Published 15 Mar 2021
Abstract
Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia is a neoplasm composed of monomorphic small mature B cells that co-express CD5, CD23 and one type of immunoglobulin light chain either kappa or lambda, which is necessary for the diagnosis. Here, we report a case in a 65 year woman with morphological diagnosis of B-Chronic Lymphocytic Leukemia. On flowcytometry analysis, immunoglobulin light chain restriction was not apparent as B cells expressed both kappa & lambda light chains without a clear monotypic population. Sequential gating on flowcytometry revealed two monoclonal B-cell populations and helped in identification of this rare case of biclonal disease in chronic lymphocytic leukemia (CLL).
Cited by 0
No indexed citations yet.
Related research
- Bone Marrow Changes Induced by Guiera Senegalensis in Acetic Acid-induced Colitis in Wistar Rats — shares topic coverage
- Chemoprotective Effect of Eugenol on Repeated dose Doxorubicin, Induced Genotoxic Lesions in Mouse Bone Marrow — shares topic coverage
- Frequency of Different Types of Leukemia in Bone Marrow- Study at a Tertiary Care Center, Lucknow — shares topic coverage
- Haematopoietic Enhancing Effect of Ethanolic Seed Extract of Citrullus lanatus (Watermelon) on Bone Marrow of Wistar Rats — shares topic coverage
- EMF Power Absorption in Bone and Bone Marrow: Mathematical Model — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.