The Hematological Profile, Hepatic Marker, and Histomorphology Effects on Canned Tomato Consumption Using Adult Male Wistar Rats

Abstract

Objective: The study investigates the effects of canned tomato consumption on the hematological profile, hepatic markers and histology. Methods: The study involved 20 male Wistar rats divided into two groups, each fed Gino tomato sachets for 21 days. The rats were anesthetized, and liver and blood were extracted. Standard laboratory analysis, light microscope, GraphPad Prism, and ANOVA were used for descriptive and statistical analysis, with a significance level of p<0.05. Results: Findings show the presence of Carbohydrates, Alkaloids, Flavonoids, reducing sugar and Resins were present, Results for PCV were 7.00±4.15 and 53.00±3.69%, Hb levels were 11.70±1.03 and 17.68±1.22g/L. (WBC) are 9.44±1.32 and 7.16±0.50g, with results significant at (p<0.05), in table 2. The results for Liver function are 12.80±2.78 and 4.80±0.58 U/l for AST, 8.60±1.33 and 5.40±0.68 U/L for ALT, Total protein 62.40±6.52 and 68.60±8.41 (g/L), and was significant at p<0.05 in table 4. The weights of the rats for the first 21 days were 81.70±3.20 and 84.50±3.46g, 102.00±3.45 and 114.90±3.84g, and 103.30±5.19 and 107.70±5.47g, with significance at week 2 in table 4, the weight after 21 days were 173.20±7.45 and 183.20±6.69g, 177.00±6.64 and 198.20±12.46g, and 189.60±8.01 and 205.40±9.90g. Conclusion: Solanum lycopersicum had no significant effect on the hematological, histological, or hepatic markers of rats fed tomato pastes, implying no effect on their weight.