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Research Article Open access CC BY 4.0

Metabolites Detected in the Crude N-Hexane Extract of Artemisia annua Linn (Asteraceae) Cultivated in Langtang, Plateau State, Nigeria

Cyril E. Manulu, Esther A. Adelakun, Jeremiah I. Abok

Chemical Science International Journal · pp. 1–6 · Published 11 Feb 2017

10.9734/CSJI/2017/28602

Abstract

Artemisia annua was grown in and harvested from Langtang, Plateau State in Nigeria. The dried pulverized aerial part of Artemisia annua was extracted with n-hexane by percolation and concentrated in vaccum at 40°C. Analysis of crude n-hexane extract by GC-MS revealed twelve major compounds, which were mostly terpenoids. These are Deoxyqinghaosu (6.85%), Arteannuic acid (3.99%), Caryophyllene oxide (4.49%), 9-Octadecenoic acid (25.54%), Camphor (2.93%), Borneol (1.48%), 5,5Dimethyl-6-methylenebicyclo[2,2,1]hept-2-yl acetate (1.18%), 2,6-dimethyl-3,5,7-octatriene-2-ol, E,E (1.48%), Carveyl acetate (0.52%), Spathulenol (1.57%), α-Cubebene (0.66%), β-Farnesene (0.57%). The result suggests that the Artemisia annua chemotypes cultivated in Langtang area of Plateau State, Nigeria, may be related to those grown in Ethiopia.

Artemisia annua L. metabolites GC-MS terpenoids

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