Potential of Indonesian Herbal Medicine, Phaleria macrocarpa (Scheff.) Boerl, for Targeting Multiple Malignancy Signaling Pathways: An Introductory Overview
Ahmad Faried, Hendrikus Masang Ban Bolly, Leri Septiani, Dikdik Kurnia, Muhammad Zafrullah Arifin, Firman Fuad Wirakusumah
European Journal of Medicinal Plants · pp. 1–17 · Published 20 Oct 2015
10.9734/EJMP/2016/20760Abstract
A wide variety of natural compounds have been recognized for targeting multiple malignancy signaling pathways and inducing apoptosis in various cancer cell lines from different origins. The chemical compositions of those substances present in plants contribute to their significant biological and medicinal value. In this review, we summarized our current findings and knowledge of bioactive compounds isolated from the Indonesian medicinal herb, Phaleria macrocarpa (Scheff.) Boerl, also known as Mahkota Dewa (MaDe) that originated from Papua province. A growing body of evidence from several countries suggests that the plant possesses potential for cancer therapy and chemoprevention. Exploring its mechanism in targeting multiple malignancy signaling pathways will provide valuable information for possible clinical applications in cancer management.
Cited by 11
O.R. Alara, S.K. Abdul Mudalip, O.A. Olalere · Journal of Applied Research on Medicinal and Aromatic Plants · 2017
A.R. Roonjho, R Muhamad, D Omar · The Journal of Animal and Plant Sciences · 2020
Dr Rosilah Ab Aziz, Izzatul Zuliana Zolkefli, Nur Atiqah Jamari · International Journal of Engineering Applied Sciences and Technology · 2020
Yoonho Choi, Sehyeon Kang, Song-Hyun Cha · Nanoscale Research Letters · 2018
Dinar Mutia Rani, Hendris Wongso, Reza Yuridian Purwoko · Phytochemistry · 2023
Ivanna Beru Brahmana, Purwanto Purwanto, Soetrisno Soetrisno · Research Journal of Pharmacy and Technology · 2024
Ivanna Beru Brahmana · AIP Conference Proceedings · 2024
Yosie Andriani, Wahdini Hanifah, Alifa Husnun Kholieqoh · Journal of Advanced Pharmaceutical Technology & Research · 2023
Hasim Hasim, Yonathan Arderian Mantik, Husnawati Husnawati · Borneo Journal of Pharmacy · 2022
Juliana Christina, Wendy Abigail, Lesley A. Cuthbertson · Journal of Holistic Nursing · 2018
Related research
- Dysregulation of Signaling Pathways Plays a Role in the Development and Pathogenesis of Hepatocellular Carcinoma — shares topic coverage
- Network-based Toxicogenomics Approach to Unraveling the Influence of Lead and Cadmium Mixture on the Development and Progression of Hypertension — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
11
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.