Biodegradation, Bioactivity and In vivo Biocompatibility Analysis of Plasma Electrolytic Oxidized (PEO) Biodegradable  Mg Implants

Mehdi Razavi; Mohammad Hossein Fathi; Omid Savabi; Daryoosh Vashaee; Lobat Tayebi

doi:10.9734/PSIJ/2014/9265

Research Article Open access CC BY 3.0

Biodegradation, Bioactivity and In vivo Biocompatibility Analysis of Plasma Electrolytic Oxidized (PEO) Biodegradable Mg Implants

Mehdi Razavi, Mohammad Hossein Fathi, Omid Savabi, Daryoosh Vashaee, Lobat Tayebi

Physical Science International Journal · pp. 708–722 · Published 7 Mar 2014

10.9734/PSIJ/2014/9265

Abstract

In this paper, a plasma electrolytic oxidation (PEO) coating was prepared on AZ91 magnesium (Mg) implant to improve its degradation resistance, bioactivity and biocompatibility. The phase composition and surface morphology of the samples were characterized using X-ray diffraction (XRD) and scanning electron microscope (SEM). The corrosion rate and the bioactivity behavior of the samples were investigated via electrochemical measurements and immersion tests in simulated body fluid (SBF). The biocompatibility of samples was evaluated both in vitro and in vivo. To performed in vitro examinations, L-929 cells were cultured on both coated and uncoated substrates, and for the in vivo study, samples were implanted into the greater trochanter of rabbits as our animal model. The results showed that the PEO coating enhanced the corrosion resistance and in vitro and in vivo biocompatibility of AZ91 Mg implants.

Plasma electrolytic Oxidation Biodegradable Mg alloy in vitro L-929 cells in vivo Biomedical applications

Cited by 20

Significant degradability enhancement in multilayer coating of polycaprolactone-bioactive glass/gelatin-bioactive glass on magnesium scaffold for tissue engineering applications

Mostafa Yazdimamaghani, Mehdi Razavi, Daryoosh Vashaee · Applied Surface Science · 2015

Nanobiomaterials in periodontal tissue engineering

Mehdi Razavi, Erfan Salahinejad, Mina Fahmy · Nanobiomaterials in Hard Tissue Engineering · 2016

In vivo biocompatibility of Mg implants surface modified by nanostructured merwinite/PEO

Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi · Journal of Materials Science: Materials in Medicine · 2015

In vivo study of nanostructured akermanite/PEO coating on biodegradable magnesium alloy for biomedical applications

Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi · Journal of Biomedical Materials Research Part A · 2014

Porous magnesium-based scaffolds for tissue engineering

Mostafa Yazdimamaghani, Mehdi Razavi, Daryoosh Vashaee · Materials Science and Engineering: C · 2017

Development of electro-co-deposited Ni–Fe(Ti,W)C nanocomposite coatings

S. Khorsand, M. Karbasi, F.S. Sayyedan · Surface Engineering · 2018

In vitro study of nanostructured diopside coating on Mg alloy orthopedic implants

Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi · Materials Science and Engineering: C · 2014

In vivo study of nanostructured diopside (CaMgSi2O6) coating on magnesium alloy as biodegradable orthopedic implants

Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi · Applied Surface Science · 2014

Degradation behavior of the MgO/HA surface ceramic nano-composites in the simulated body fluid and its use as a potential bone implant

Vida Khalili, Jan Frenzel, Gunther Eggeler · Materials Chemistry and Physics · 2021

Anticorrosion and Cytocompatibility Assessment of Graphene-Doped Hybrid Silica and Plasma Electrolytic Oxidation Coatings for Biomedical Applications

Juan P. Fernández-Hernán, Antonio J. López, Belén Torres · ACS Biomaterials Science & Engineering · 2021

In vitro Impact Assessment of Aqueous Extract of Sida cordifolia Linn. Upon Rat Spermatozoa Parameters — shares topic coverage
In vitro Probiotic Potential of Autochthonous Lactic Acid Bacteria and Microbiology of Kunu Made from Mixed Grains — shares topic coverage
In vitro Investigation of Antimicrobial, Antitumor and DPPH Reduction Capacity of the Methanolic Extract of Scoparia dulcis — shares topic coverage
Antifungal Efficacy of Zinc Oxide Nanoparticles against Anthracnose and Southern Blight Disease in Green Gram — shares topic coverage
Evaluation of Fungicides against Sheath Rot Disease of Rice: An In vitro Study — shares topic coverage

Access this article

View at publisher

Cite this article

Mehdi Razavi, Mohammad Hossein Fathi, Omid Savabi, Daryoosh Vashaee, Lobat Tayebi (2014). Biodegradation, Bioactivity and In vivo Biocompatibility Analysis of Plasma Electrolytic Oxidized (PEO) Biodegradable Mg Implants. Physical Science International Journal , 708–722. https://doi.org/10.9734/PSIJ/2014/9265

Affiliations

Mehdi Razavi — Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran and School of Materials Science and Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA and School of Electrical and Computer Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA
Mohammad Hossein Fathi — Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran and Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Omid Savabi — Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
Daryoosh Vashaee — School of Electrical and Computer Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA
Lobat Tayebi — School of Materials Science and Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA and School of Chemical Engineering, Oklahoma State University, Stillwater, OK 74078, USA

Metrics

0
Views: 0
Downloads: 20
Citations: 0
Outbound

Full metrics

Article metrics

Real usage data collected on this platform.

0

Page views

0

PDF downloads

0

Outbound clicks

20

Citations

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

No views recorded yet.

Traffic sources

Referring site, by host.

No traffic recorded yet.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.