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All published articles 154

Seroprevalence of Hepatitis B and C Viruses among Grassroots Football Players in a Selected Community in Jos, Plateau State

David Paul Nyam, Duguru John Mary, Davwar Mark Pantong, Makpu Dan Jireh, Atta Okwute, Mchenry Ifeanyi Stephen, Zawaya Paul Kefas, Okorie Chidebere Michael, Omaiye One Patience, Andrew Nzolaningi Godiya, Mamot James Isaiah, Asor Msugh Paul, Maurice Wadzani Solomon, Akpa Ojile Philip, Dayom S. Pannan & Okeke N. Edith · International Research Journal of Gastroenterology and Hepatology · 2025

Introduction: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections remain significant global health challenges, particularly in sub-Saharan Africa where the burden is disproportionately high. Contact sports, such as football, especially at the grassroots level where sta...

Open access Research Article 10.9734/irjgh/2025/v8i1115

Impact of Methamphetamine on Electrolytes, Lipid Profile, and Protein Metabolism: Insights into Biochemical Alterations and Toxicity Mechanisms

Umoren, EB, Melford FI, Nyenke CU & Etim OE · International Research Journal of Gastroenterology and Hepatology · 2025

Background: Methamphetamine (METH) is a strong stimulant of the central nervous system. It is well known for its recreational usage and significant potential for misuse. It is also implicated to cause physiologic changes on the gastrointestinal health. Research Objectives: The st...

Open access Research Article 10.9734/irjgh/2025/v8i1114

Prevalence and Risk Factors of Hepatitis B Virus Infection among Patients in Tertiary Healthcare Facilities in Nasarawa State, Nigeria: A Cross-Sectional Study

Aboh Ochapa Victor, Adamu I Akyala, Agieni Ashem Godwin, Bello Folake Saidat, Ibrahim Ismaila, Jaggu Ruth Awayimbo & Henry Chukwunonso Egbu · International Research Journal of Gastroenterology and Hepatology · 2025

Background: An estimate by the WHO in 2022 has it that 254 million people were living with chronic hepatitis B infection with a reported death of 1.1 million individuals. In Nigeria, hepatitis B virus (HBV) infection remains a critical public health challenge. This challenge is e...

Open access Research Article 10.9734/irjgh/2025/v8i1113

Therapeutic Effects of Cucurbita pepo (Pumpkin) Fruit Pulp and Seeds Methanol Extracts Against CCl₄ Induced Hepatotoxicity in Wistar Rats

Tukur S. Ahmad, Mairiga J. Peters, Bawa Y. Muhammed, Yunusa Rahima & Haruna G. Sunday · International Research Journal of Gastroenterology and Hepatology · 2025

This study was aimed at assessing the therapeutic potential of Cucurbita pepo (Pumpkin) Pulp and Seeds Methanol extract against CCl4 induced hepatotoxicity in wistar rats. The phytochemical screening, analyses of liver function and haematological parameters were carried out follo...

Open access Research Article 10.9734/irjgh/2025/v8i1112

Diagnostic Performance of Rapid Screening and ELISA Methods in the Detection of Hepatitis B Virus Surface Antigen among Patients Attending Tertiary Healthcare Facilities in Nasarawa State, Nigeria

Aboh Ochapa Victor, Adamu I Akyala, Agieni Ashem Godwin, Bello Folake Saidat & Ibrahim Ismaila · International Research Journal of Gastroenterology and Hepatology · 2025

Background: Hepatitis B Virus (HBV) infection is a global public health problem. It is estimated that 820,000 deaths occur every year and 3.6% of the global population including over 6 million children under the age of 5 is affected by chronic HBV infection and approximately 2 bi...

Open access Research Article 10.9734/irjgh/2025/v8i1111

Effects of Cement Dust Exposure on Liver Function among Construction Workers in Akala Express

Oniye Adesola Helen, Agbaje Boluwatife Temilade, Ojebode Emmanuel Olwapelumi, Adesina Beatrice Ebun, Amusan Festus Olatunbosun, Inegbenebor Sylvester Ehilenbalu, Alabi Raphael & Akpan Richard Peter · International Research Journal of Gastroenterology and Hepatology · 2025

Introduction: Exposure to cement dust presents serious threats to one's health at work, especially for construction workers. Its possible effects on liver function are still little understood, despite the well-established benefits on respiratory and skin health. Aim/Objective: Th...

Open access Research Article 10.9734/irjgh/2025/v8i1110

Hepatoprotective Effect of Honey and Green Tea on Atrazine Induced Hepatotoxicity in Albino Wistar Rats

Obisike, U.A. & Abraham, A.J. · International Research Journal of Gastroenterology and Hepatology · 2025

Aim: To evaluate the hepatoprotective effect of green tea and honey on atrazine induced hepatotoxicity in albino Wistar rats. Study Design: Experimental study. Place and Duration of Study: Department of Clinical Chemistry and Department of Anatomy, Rivers State University, Port H...

Open access Research Article 10.9734/irjgh/2025/v8i1109

Evaluation of the Pharmacological Properties of Dichrostachys cinerea Hydroalcoholic Extract on the Contractility of Taenia Coli Isolated from Guinea Pigs

Reine Raïssa Rolande Aworet Samseny, Ericka Lorleil Mayindza Ekaghba & Line Edwige Mengome · International Research Journal of Gastroenterology and Hepatology · 2025

Aims: Dichrostachys cinerea is a plant use for his several properties,including the treatment of abscesses, eczema, gonorrhea, rheumatism, gingivitis, dental caries, epilepsy, as diuretic and laxative; against otitis, umbilical hernia, malaria in children. No study shows the laxa...

Open access Research Article 10.9734/irjgh/2025/v8i1108

Comparison of Intravenous and Topical Injection Administration Mesenchymal Stem Cell Secretome to Restrain Gastrointestinal Anastomosis Leakage: A Review

Joko Wibowo Sentoso, Agung Putra, Ida Bagus Budhi SA, Anung Noto Nugroho & Suryo Wahyu Raharjo · International Research Journal of Gastroenterology and Hepatology · 2025

Intestinal anastomosis is one of the most commonly performed gastrointestinal surgical procedures, especially in emergencies and is commonly performed in elective procedures when resection is performed for benign or malignant lesions of the gastrointestinal tract. One of the impo...

Open access Research Article 10.9734/irjgh/2025/v8i1107

Prevalence and Risk Factors for Metabolic-dysfunction Associated Fatty Liver Disease in South Indian Population

Dhivya E, Kandasamy Kumar E, Poppy Rejoice, Shafique A & Geetha D · International Research Journal of Gastroenterology and Hepatology · 2024

Background: Metabolic associated fatty liver disease (MAFLD) is a new definition proposed by the global consensus panel in 2020 for liver disease associated with known metabolic dysfunction. Based on new diagnostic criteria, we aimed to investigate its prevalence and risk factors...

Open access Research Article 10.9734/irjgh/2024/v7i1106

Role of Routine Bone Marrow Biopsy Preoperatively in Non Cirrhotic Portal Hypertension

Karthik Chalamalasetti, Sugaprakash Sankareswaran, Prabhakaran Raju & Sugumar Chidambaranathan · International Research Journal of Gastroenterology and Hepatology · 2024

Background: A bone marrow biopsy is routinely done prior to surgical intervention in patients with Extrahepatic portal venous obstruction (EHPVO) and Non-Cirrhotic portal fibrosis (NCPF) to rule out other aetiologies pertaining to pancytopenia. However, there are no guidelines fo...

Open access Research Article 10.9734/irjgh/2024/v7i1105

Complex Interplay of Cardiac, Hepatic, and Renal Dysfunction in a Patient with Extra-hepatic Portal Vein Obstruction and Rheumatic Mitral Stenosis: A Case Report

Jasper Victoria Leelarani Martinraj & Keren Ann George · International Research Journal of Gastroenterology and Hepatology · 2024

This case report presents a 31-year-old male with a complex interplay of cardiac, hepatic, and renal dysfunction, characterized by extra-hepatic portal venous obstruction (EHPVO), decompensated chronic liver disease (DCLD), and rheumatic heart disease (RHD) with severe mitral ste...

Open access Research Article 10.9734/irjgh/2024/v7i1104

Effect of Age on Colonic Damage Induced by Cadmium Exposure in Female Wistar Rats

Serah Funke Ige, Ibukunoluwa Victor Fayemi, Julius Ayomide Ayoola, Mariam Ololade Olasupo, Olajumoke Deborah Ogunleye, Gbenga Opeyemi Owolabi & Taiwo Adebayo Ajagbe · International Research Journal of Gastroenterology and Hepatology · 2024

Background: Cadmium, a known genotoxic metal, has been shown to worsen colonic damage in both animal models and human studies. Research has indicated that cadmium accumulation in the colon results in mucosal damage, inflammation, disrupted immune responses, and an increased risk...

Open access Research Article

Seroprevalence of Helicobacter pylori Infection among Adults in Port Harcourt Metropolis, Nigeria

Chidi L.C. Ndukwu, Owhorchukwu Amadi-Wali & Roseanne Adah Ikpeama · International Research Journal of Gastroenterology and Hepatology · 2024

Introduction: Helicobacter pylori is a highly evolved and adapted pathogen, notorious for having infected half of all the people in the world. It is linked as a causative agent for numerous benign and malignant diseases of the digestive tract, such as peptic ulcer disease (PUD) a...

Open access Research Article

Oxidative Stress Markers in Malaria Patients: Assessing the Impact of Parasitaemia Severity at Rivers State University Teaching Hospital, Nigeria

Odum, J., Obisike, U.A. & Elekima, I. · International Research Journal of Gastroenterology and Hepatology · 2024

Aim: The present study aimed to assess the levels of some oxidative stress markers in malaria parasite-infected subjects attending Rivers State University Teaching Hospital, Port Harcourt, Nigeria. Background: Malaria can be fatal, the severity of malaria infection is closely lin...

Open access Research Article