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All published articles 268

Insilico Docking Analysis of Antimalarial and Anticancer Potentials of a Hydrazone Derivative of 2-Amino-4-Thiazoleacetic Acid Hydrazide

Ngozi Patricia Ebosie, Beniah Obinna Isiuku & Pauline Amaka Nnagbo · South Asian Research Journal of Natural Products · 2025

2-amino-4-thiazoleacetic acid hydrazide (ATAH) was prepared from the reaction of ethyl-2-amino-4-thiazoleacetate with hydrazine hydrate. The hydrazone derivative, 2-(2-amino-1,3-thiazol-4-yl)-N'-[(E)-(4-methoxyphenyl)methylidene]acetohydrazide (ATAPH) was synthesized by the conde...

Open access Research Article 10.9734/sarjnp/2025/v8i2197

Antipyretic Medicinal Plants of Bangladesh: An Ethnobotanical and Traditional Perspective

Rajone Ahamed Mahin, Masfique Uddin Chowdhury, Sanjana Afrin, Tahmina Haque Nuha, Umme Nusrat Jahan Nimmee, Nafisa Rumman, Samia Afroz, Jannatul Ferdous Jarin, Md. Mustafiz Chowdhury, Mohammed Kamrul Hossain & Nawreen Monir Proma · South Asian Research Journal of Natural Products · 2025

Background: Bangladesh boasts an impressive array of plant life, contributing to its unique ecological landscape. For centuries, medicinal plants have been central to the traditional healing practices of the Bangladeshi people, serving as a vital resource in their treatment of va...

Open access Research Article 10.9734/sarjnp/2025/v8i2195

Molecular Spectroscopic (FTIR and UV-Vis) and Hyphenated Chromatographic (GC–MS) Characterization of Bioactive Compounds Present in Different Solvent Fractions of Extract of Leaf of Cola hispida Brenan & Keay Sterculiaceae

Goodnews Onyedikachi Ikeh, Njideka Ifeoma Ani, Vincent Uchechukwu Ude, Jude Kosisochukwu Onyia, Charles C. Diovu & Rita Chiamaka Okpoto · South Asian Research Journal of Natural Products · 2025

Cola hispida Brenan & Keay (Sterculiaceae), a tropical plant native to West and Central Africa, is widely used in traditional medicine for its therapeutic properties, yet its phytochemical composition remains underexplored. This study investigates the bioactive compounds in d...

Open access Research Article 10.9734/sarjnp/2025/v8i2194

Phytochemical Analysis, Antimicrobial, Cytotoxic and Antioxidant Activities of Oenanthe javanica

Humayun khan, Muhammad Suleman khan, Alamgir khan, Muhammad Jamshed, Zama Jan, Uzair khan & Sara Ali · South Asian Research Journal of Natural Products · 2025

Medicinal plants are an integral part of life in many communities. They are source of vital therapeutic aid for assuaging human ailments and that is chiefly due to existence of biologically active phytochemicals. Oenanthe javanica, aquatic perennial herb, known for its medicinal...

Open access Research Article 10.9734/sarjnp/2025/v8i2193

Impact of Eurycoma longifolia (Physta®) on Gut Microbiome Composition: A Case Study Using Precision Microbiome Profiling

Anne-Grethe G. Reichelt, Priya Kandanur, Annie George & Sasikala M. Chinnappan · South Asian Research Journal of Natural Products · 2025

The gut microbiome plays a critical role in maintaining human health particularly via the gut-brain axis by regulating metabolic, immune and neuroendocrine functions. The supplementation of pro and prebiotics along with certain nutrition may benefit gut microbial diversity. Early...

Open access Research Article 10.9734/sarjnp/2025/v8i2191

Effect of Cajanus cajan (L) Millsp. leafy Extracts on Haematological Function, Oxidative Stress, and Inflammatory Markers in Spleen Tissue of Plasmodium berghei-infected Mice

Spencer O. S., Akinnuoye B. O. & Oyeleye I. S. · South Asian Research Journal of Natural Products · 2025

Objective: Oxidative stress and inflammation are common complications of malaria, with the infection’s effects ranging from simple to life-threatening multiple organ failure. This study investigates the protective effects of Cajanus cajan leafy extracts on haematological dysfunct...

Open access Research Article 10.9734/sarjnp/2025/v8i2192

Pharmacological Assessment of the Ormosia robusta Methanol Leaf Extract against Free Radicals, Cytotoxicity and Inflammation: An In-vitro and In-silico Investigation

Md. Lokman, Md. Liakot Ali, Saad Ahmed Sami, Nafisa Binte Mannan, Mohammad Rashedul Islam, Nawreen Monir Proma & Mohammed Kamrul Hossain · South Asian Research Journal of Natural Products · 2025

Aims: Ormosia robusta (O. robusta) grown mainly in East Asia is known for its popular traditional uses. The objective of this research is to examine the phytochemical makeup of methanol leaf extract of O. robusta (MELOR) and assess its in vitro antioxidant, cytotoxic, and anti-in...

Open access Research Article 10.9734/sarjnp/2025/v8i1190

Synthesis, Characterization of Spectral, Thermal and Biological Investigations of Co (II) and Zn (II) Complexes with New Aminopyrimidine Schiff Base Ligand

D.T. Sakhare · South Asian Research Journal of Natural Products · 2025

The new Heterocyclic Schiff base ligand Co (II) and Zn (II) complexes. The Schiff base ligand derived from 2-amino-4-hydroxy-6-methylpyrimidine and 2-Hydroxy-5-chlorobenzaldehyde to form Schiff base (L) was synthesized and characterized by IR and electronic spectroscopy, melting...

Open access Research Article 10.9734/sarjnp/2025/v8i1189

Phytochemical Analysis and Antibacterial Assessment of Pineapple (Ananas comosus) Peel Extract

Audric Cleine L. Castro, Artha Clarice C. Lubido, Ayeszha Khirzt A. Balderas, Rainier Klein P. Gonzales & Ian Jay P. Saldo · South Asian Research Journal of Natural Products · 2025

Aims: This study assessed the phytochemical composition and antibacterial properties of pineapple peel (Ananas comosus), a significant by-product of pineapple production, which is often discarded despite its potential health benefits. Pineapple peels constitute 30-42% of the frui...

Open access Research Article 10.9734/sarjnp/2025/v8i1188

In vitro and In vivo Evaluation of Anti-inflammatory Activity of Methanol Stem Bark Fraction of Morinda lucida BENTH

Cyril C Adonu, Romanus C Omeh & Ibeabuchi J. Ali · South Asian Research Journal of Natural Products · 2025

Aims: To investigate the anti-inflammatory potentials of the methanol extract fraction of Morinda lucida stem bark. Methodology: Pulverized dried M. lucida stem bark was cold macerated in methanol for 72 hours. The liquid extract was filtered and then concentrated to a semi solid...

Open access Research Article 10.9734/sarjnp/2025/v8i1187

Antioxidant and Anti-ulcerogenic Effect of Chloroform and Methanol Partitioned Leave Extracts of Harungana madagascariensis on Wistar Albino Rats: A Comparative Analysis

Asadu, Chidimma Lilian, Ugwu, Obiora Celestine, Uroko Robert Ikechukwu, Eze Chidozie Peace, Umeakuana Chidinma Doris, Uzoefuna Chima Casmir, Ogbonna Chidera Gloria, Offia Ogbonna Raymond, Idokoja Levi Onyebuchi, Peter Princess Oluchukwu & Anosike Chioma Assumpta · South Asian Research Journal of Natural Products · 2025

Background: This research investigated the antioxidant and anti-ulcerogenic potentials of chloroform and methanolic leave extracts of Harungana Madagascariensis leave. Antioxidants are substance that prevents or slows down the damage caused by free radicals. An ulcer is an open s...

Open access Research Article 10.9734/sarjnp/2025/v8i1186

Phytochemical, Mineral and Vitamin Profile of Different Aqueous Layers of Justicia carnea and Mucuna pruriens

Onuabuchi Nnenna Ani, Oyiyechukwu Elizabeth Chikelu, Innocent Izuchukwu Ujah & Cosmas Ezekaibeya Achikanu · South Asian Research Journal of Natural Products · 2025

For ages, plants have been utilized for both nutritional and medicinal purposes. Mucuna pruriens and Justicia carnea are two prominent examples, traditionally used in medicine. This study examined the phytochemical, mineral, and vitamin profiles of the supernatant and down layers...

Open access Research Article 10.9734/sarjnp/2025/v8i1185

Innovative Techniques for Natural Product Isolation: Bridging Tradition and Modernity

Sani M. Isyaka, Ferdinand Chidinma, Odih Christian, Akabuogu O. Wilson, Adegbenro A. Tosin, Oluwashola S. Adetokunbo & Abdullahi M. Abdullahi · South Asian Research Journal of Natural Products · 2025

Naturally occurring substances from prebiotic, microbial, plant and animal sources have always piqued human curiosity. Plant extracts of various parts have been used extensively in traditional medicines, perfumes, food flavorings, and preservatives. They are also more frequently...

Open access Research Article 10.9734/sarjnp/2025/v8i1183

Anti-Inflammatory Effects of a Cocoyam-Bambara Groundnut-soya Bean Flour Blend in Streptozotocin-Induced Diabetic Rats

Uro-Chukwu, H.C, Ezekwe, A.S, Okari, K. A, Uro-Chukwu, F.N.C, Oko, C.I & Uro-Chukwu, F.C.U · South Asian Research Journal of Natural Products · 2025

Background: Diabetes mellitus has assumed a Public Health prominence as a result of the global prevalence, mortality and disability. With effective and affordable management not universally in focus, as a result of the huge financial burden associated with its management, attenti...

Open access Research Article 10.9734/sarjnp/2025/v8i1184

Preparation and Characterization of Some Oxazolidine-5-one Derivatives and Evaluation of their Biological Activity

Mohammed Jwher Saleh, Jamil Nadhem Saleh, Khalid Al-Badrany, Mohammeed. H. Yaseen, Marwan Hasan Ali & Abdul Wahed Abdul Sattar Talluh · South Asian Research Journal of Natural Products · 2025

The research included the preparation of new compounds of oxazolidine-5-one from the reaction of prepared Schiff bases with chloroacetic acid in the presence of dioxane as a solvent. The preparation used the sublimation method, and the reaction was monitored and described by dete...

Open access Research Article 10.9734/sarjnp/2025/v8i1181