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All published articles 212

Effect of Cadmium and Soursop Leave on the Stomach Histology of Adult Albino Rats

Ajanwachukwu Wilson Ogbonna · Asian Journal of Research and Reports in Gastroenterology · 2026

This study investigated the effect of cadmium exposure and Annona muricata (soursop) leaf extract on the stomach histology of adult albino rats. Cadmium is a well-known environmental toxicant associated with oxidative stress and tissue damage, while Annona muricata is a medicinal...

Open access Research Article 10.9734/ajrrga/2026/v9i1226

Synergistic Effects of Lead on Acetic Acid-induced Colitis Via Oxidative Damage in Male Wistar Rats

Taiwo Adebayo Ajagbe, Serah Funke Ige, Oluwaseun Grace Adebayo, Adetoun Bunmi Aribatise, Anthony Ifeoluwa Adeyefa, Faith Eniola Adelakun, Mathew Ayobami Fatoki, Omotola Deborah Olatunji, Christianah Damilola Ayeni & Aliyat Nafiu Olanrewaju · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Environmental lead exposure may contribute to gastrointestinal injury through oxidative and inflammatory mechanisms. This study investigated whether oral lead exposure aggravates acetic acid-induced colitis in male Wistar rats. Methods: Forty-eight rats were allocated...

Open access Research Article 10.9734/ajrrga/2026/v9i1225

Gastroprotective Effects of Nigella sativa (Black Seed) Oil on Serum Biochemical Markers and Gastric Histoarchitecture in Ethanol-Induced Gastric Ulceration in Wistar Rats

Aniah Julius Akomaye, Mohammed Ahmed Mirwa, James Rimamtsab & Inyang Bassey Atte · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Peptic ulcer disease remains a major global gastrointestinal disorder, and ethanol-induced gastric ulceration in rodents is a well-validated model for studying mucosal injury driven by oxidative stress, inflammation, and disruption of gastric mucosal defences. Convent...

Open access Research Article 10.9734/ajrrga/2026/v9i1224

Green-synthesised Nanoparticles for Gastric Ulcer Therapy: Mechanistic Promise, Preclinical Evidence and Translational Barriers

Taiwo Adebayo Ajagbe, Serah Funke Ige, Faith Eniola Adelakun, Christianah Damilola Ayeni, Mathew Ayobami Fatoki, Omotola Deborah Olatunji, Oluwadunsin Elizabeth Adediji, Folashayo Lucilia Edun & Khadijat Pamilerin Adeyemo · Asian Journal of Research and Reports in Gastroenterology · 2026

Gastric ulcer treatment is clinically effective when the causal pathway is identified and managed, yet antibiotic resistance, incomplete mucosal recovery, recurrent injury and treatment-related burden continue to motivate adjunctive strategies. Green-synthesised nanoparticles are...

Open access Research Article 10.9734/ajrrga/2026/v9i1223

Perception of Nutritional Management of Peptic Ulcer Disease: A Cross-Sectional Survey in Umuahia North Local Government Area of Abia State, Nigeria

Elekeh Rosemary Ichita, Ibeh Chiderah Favour & Uka-kalu Ezinne · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Peptic ulcer disease remains an important gastrointestinal condition associated with recurrent symptoms and reduced quality of life. Dietary practices may influence symptom control and patient behaviour, yet misconceptions about appropriate nutritional management pers...

Open access Research Article 10.9734/ajrrga/2026/v9i1221

Impacted Nasogastric Tube Embedded in the Oropharyngeal Muscle: A Rare Mechanical Complication of Long-Term Enteral Feeding

Vishal Bodh, Ajay Ahluwalia & Brij Sharma · Asian Journal of Research and Reports in Gastroenterology · 2026

Aims: Nasogastric tube (NGT) insertion is a commonly performed procedure for enteral nutrition and gastric decompression. Although it is generally considered safe, complications ranging from minor mucosal injury to perforation, infection and vascular injury have been reported. Me...

Open access Research Article 10.9734/ajrrga/2026/v9i1222

Metastatic Melanoma to the Common Bile Duct Presenting as Obstructive Jaundice: A Case Report and Literature Review

Navdeep Kaur, Akhila Aravind, Shou Jiang Tang & Neha Varshney · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Metastatic melanoma involving the biliary tract is exceedingly rare and is often diagnosed at a late stage. Awareness of this entity is essential in patients with a prior history of melanoma who present with biliary symptoms. Case Presentation: A 35-year-old Caucasian...

Open access Research Article 10.9734/ajrrga/2026/v9i1220

Intrahepatic Cholangiocarcinoma Complicated by Non-Cirrhotic Portal Hypertension and Variceal Bleeding: A Case Report

AMKHAOU Fatima, N. Najimi & Wafaa Badre · Asian Journal of Research and Reports in Gastroenterology · 2026

Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver malignancy after hepatocellular carcinoma and is often diagnosed at an advanced stage because early symptoms are non-specific. Portal hypertension is an uncommon complication of ICC and is usually relat...

Open access Research Article 10.9734/ajrrga/2026/v9i1219

Evaluation of the Antiulcer Effects of Ethanol Extract of Rinorea subintegrifolia Leaves in Male Wistar Rats

Peter Osezele Okonudo & Celina Odion Ogbease · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Medicinal plants remain important sources of bioactive compounds for the management of gastrointestinal disorders, and Rinorea subintegrifolia is used ethnomedicinally for stomach disorders in parts of Edo State, Nigeria. Aim: This study evaluated the antiulcer effect...

Open access Research Article 10.9734/ajrrga/2026/v9i1218

Assessment of the Knowledge, Attitudes, and Practices of Resident Physicians in Gastroenterology and Infectious Diseases Regarding Digestive Manifestations of HIV Infection: A Study at the Ibn Rochd University Hospital of Casablanca

Zineb Boukhal, Oscar Ntiranyibagira, Meryem Thaili, Fatima Zahra El Rhaoussi, Mohamed Tahiri, Fouad Haddad, Wafaa Hliwa, Ahmed Bellabah & Wafaa Badre · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Human immunodeficiency virus (HIV) infection is closely associated with a wide range of frequent gastrointestinal manifestations, which may significantly affect the quality of life of people living with HIV (PLHIV). These digestive disorders may result from the infect...

Open access Research Article 10.9734/ajrrga/2026/v9i1217

Adalimumab-induced Cutaneous lupus in Crohn’s Disease: A Case Report

Fatima Machayi, Najat Bouhdoud, Asmaa Sadik, Hala Aouroud, Oussama Nacir, Fatima Ezzahra Lairani, Adil Ait Errami, Sofia OUBAHA, Zouhour Samlani & Khadija Krati · Asian Journal of Research and Reports in Gastroenterology · 2026

Lupus induced by tumor necrosis factor-alpha (anti-TNFα) inhibitors is an uncommon yet well-documented paradoxical event in patients treated for inflammatory bowel disease. We describe the case of a 39-year-old woman with ileocolonic Crohn’s disease who, ten weeks after starting...

Open access Research Article 10.9734/ajrrga/2026/v9i1216

Late-Onset Systemic Lupus Erythematosus Presenting as Acute Bowel Obstruction Due to Mesenteric Panniculitis and Severe Pancytopenia: A Case Report

Safaa Mhaber, Safaa Mourabit, Mina Moudatir, Khadija Echchilali, Meriem Benzakour & Hassan El Kabli · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Systemic lupus erythematosus (SLE) with onset after the age of 50 years accounts for approximately 10–20% of cases and is often associated with atypical clinical features and delayed diagnosis. Gastrointestinal involvement as an initial manifestation is uncommon, and...

Open access Research Article 10.9734/ajrrga/2026/v9i1214

Giant Gastric Trichobezoar: A Rare Cause of Chronic Epigastric Pain

Fatima Machayi, Khaoula Haij, Asmaa Sadik, Hala Aouroud, Oussama Nacir, Fatima Ezzahra Lairani, Adil Ait Errami, Sofia OUBAHA, Zouhour Samlani & Khadija Krati · Asian Journal of Research and Reports in Gastroenterology · 2026

Gastric trichobezoar is a rare cause of chronic digestive symptoms and gastric outlet obstruction, predominantly affecting young females. We report the case of an adolescent presenting with chronic epigastric pain and a large gastric mass. Imaging by abdominal computed tomography...

Open access Research Article 10.9734/ajrrga/2026/v9i1215

Ameliorative and Protective Potential of Elaeis guineensis on the Small Intestine of Adult Mice Exposed to Diazepam Toxicity

O. H. Blackie, O. C. Ogbe, W. O. Ajanwachukwu, F. F. Blackie, S. B. Olukayode, W. O. Ohiwerei & T. T. Oladele · Asian Journal of Research and Reports in Gastroenterology · 2026

The small intestine plays a vital role in digestion, nutrient absorption, and immune defense, and its structural integrity is essential for maintaining gastrointestinal health. However, exposure to certain xenobiotics, including benzodiazepines such as diazepam, may induce oxidat...

Open access Research Article 10.9734/ajrrga/2026/v9i1212

Endoscopic Biliary Drainage in Malignant Biliopancreatic Strictures: Clinical Characteristics and Therapeutic Management

Sanaa, Berrag · Asian Journal of Research and Reports in Gastroenterology · 2026

Background: Malignant biliopancreatic strictures are a frequent cause of obstructive jaundice and are associated with poor prognosis. Their management remains complex, particularly in cases of hilar involvement, advanced disease, or poor performance status. Endoscopic biliary dra...

Open access Research Article 10.9734/ajrrga/2026/v9i1213