Acetaminophen is a highly used over-the-counter drug, and a good number of drug-related liver necrosis are associated with high doses of acetaminophen. In the last decade, drug-related liver necrosis has been the most reported form of liver disease. In view of this, our research...
Aims: This research work aimed to determine the effect of methanolic Acacia nolitica stem bark extract on liver functions in alloxan induced diabetic rats. Methodology: Thirty (30) young albino rats were grouped into six (6), comprising of five (5) rats per group. Diabetes was in...
Background: NAFLD (non-alcoholic fatty liver disease) is a highly frequent condition. Data on the epidemiology of non-alcoholic fatty liver disease (NAFLD) is scarce, especially in underdeveloped nations like Bangladesh. Although many people have risk factors for NAFLD, the major...
Introduction: Minimal hepatic encephalopathy (EHM) is a frequent and severe complication of liver disease with a poor prognosis. It is responsible for an altered quality of life for patients. However, it is a poorly understood complication. There is no consensus on the diagnosis...
Background: Worldwide, more than 170 million persons have hepatitis C virus (HCV) infection, of whom 71 million have chronic infection. Egypt is the country with the highest HCV prevalence worldwide–antibody prevalence in Egypt was estimated at 11.9% in a 2018 meta-analysis with...
Aims: To determine the distribution and prevalence of markers of HBV infection among HIV-positive patients attending Defence healthcare facility for treatment in Abuja, Nigeria. Study Design: A cross sectional study. Place and Duration of Study: Defence Headquarters (DHQ) Medical...
Biliary fistulas are entities whose etiology can be diverse ranging from iatrogenic to infectious. The site of origin of fistula can be from small biliary radicals to larger biliary ducts. Surgical treatment of fistulas are often difficult owing to small size of radicals and sect...
Aims: The current study was designed to determine a local reference range of serum Alanine (ALT) and Aspartate (AST) activities and De Ritis ratio amongst apparently healthy secretors and non-secretors of ABH substances within Uyo, Akwa Ibom State, Nigeria, aged between 20 to 60...
Introduction: Successful interferon free (IFN –free) treatment for hepatitis C patients are associated with improvement of liver function and blood parameters. To what extent of improvement do we see in compensated cirrhotics is unknown. Aim: To study liver function parameters i...
The liver is a major organ and plays a vital role in general physiology of human. Its pathology and abnormality will affect the normal wellbeing of human. This study was designed to determine the factors affecting liver size in adults of 18-50yrs from 2008-2012 in selected hospit...
Background: Hemostatic systems in cirrhotic patients are delicately balanced between pro- and anticoagulant factors and can be easily tipped to a hypo- or hypercoagulable status, resulting from decreased levels of procoagulant and anticoagulant factors synthesized by hepatocytes...
Introduction: Splenic hydatidosis is a rare clinical entity, yet the spleen is the third most affected organ after the liver and lungs. Objectives: The aim of our work is to study the epidemiological, clinical and paraclinical characteristics as well as the place of medical, inst...
Background: Budd Chiari Syndrome denotes a group of rare diseases which have been studied with considerable interest by clinicians across the world. The clinical presentation and investigation results vary in most cases making the diagnosis a challenge. Although the treatment pro...
Aim: The current study assessed the association between Pyridoxal-5'-phosphate (PLP) levels, liver and serum activities of aminotransferases (ALT and AST) and De Ritis ratio (DRR) in ten subjects with alcoholic hepatitis (test group -TG) and 10 healthy subjects without alcoholic...
Introduction: There are different anatomical variations of cystic artery. In this article we report a case with presence of a rare number of arteries supplying the gallbladder. Variations in the cystic artery and its branches are clinically significant for General and Hepatobilia...