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All published articles 118199

Novel Salts of Sunitinib an Anticancer Drug with Improved Solubility

Sangeeta Sangwan, Tapas Panda, Ram Thiamattam, Sharwan K. Dewan & Rajesh K. Thaper · International Research Journal of Pure and Applied Chemistry · 2014

Polymorph, co-crystal and salt screening experiments were carried out to identify novel solid forms with the improved physicochemical properties, particularly water solubility in the present case. Co-crystal formation was evaluated with urea and nicotinamide. These coformers do n...

Open access Research Article 10.9734/IRJPAC/2015/13578

A Validated RP-HPLC-UV Method for Simultaneous Estimation of Ceftriaxone and Sulbactum in Rat Plasma

B. M. Gurupadayya & N. S. Disha · International Research Journal of Pure and Applied Chemistry · 2014

A reverse phase-liquid chromatographic method with UV detection is developed for simultaneous estimation of ceftriaxone sodium and sulbactam sodium in rat plasma. A simple protein precipitation technique was employed for the extraction of drugs from blank plasma. Chromatographic...

Open access Research Article 10.9734/IRJPAC/2015/12177

Thermo-stable, Calcium Independent Alpha Amylase from Two Bacillus species in Afar, Ethiopia

T. W. Atsbha, Gulelat D. Haki, S. Abera & T. B. Gezmu · International Research Journal of Pure and Applied Chemistry · 2014

Thermostable enzymes play a major role in the food industry. Two isolates (named as TGS1 and TGS2), which were later identified as Bacillus sp., were able to produce alpha amylase at a higher temperature (45-60⁰C). The enzymes from the microorganisms were characterized at differe...

Open access Research Article 10.9734/IRJPAC/2015/14970

Method Development for Chiral Purification of Racemic Clopidogrel Using Chiral Stationary Phase

Sangeeta Sangwan, Sharwan K. Dewan & Rajesh K. Thaper · International Research Journal of Pure and Applied Chemistry · 2014

HPLC method was developed for resolution of racemic clopidogrel into its chirally pure enantiomer of interest. Screening experiments were performed using amycoat and cellucoat analytical chiral stationary phases in organic solvent based polar and nonpolar eluents in various combi...

Open access Research Article 10.9734/IRJPAC/2015/14075

The Relationship between Electrical Conductivity and Growth of Gramineae with Varied Tolerance to Sodic Saline Condition-selectivity of K+, Ca2+, and Mg2+ over Na+ in Puccinellia chinampoensis Ohwi

T. Yoshida, K. Namioka, L. Zhao, H. B. Wang, A. Sato, A. K. Xu, M. Q. Zhao, B. L. Qi, X. M. Guo & S. Kawai · International Journal of Plant & Soil Science · 2014

The characteristics of metal macronutrients absorption (K+, Ca2+, Mg2+) over Na+ in the rhizosphere of sodic soils of Puccinellia chinampoensis Ohwi (P. chinampoensis) was investigated and compared with barley and oat. P. chinampoensis is a tolerant plant for sodic conditions. In...

Open access Research Article 10.9734/IJPSS/2015/13699

Soilless Nursery Media for African Oil Bean (Pentaclethra macrophylla Benth) Seedling Production

N. Onwubiko, A. Ezeigbo, C. Cookey, E. Nwokeji, N. Adikuru, C. Tom & V. Onyia · International Journal of Plant & Soil Science · 2014

African oil bean (Pentaclethra macrophylla) is an important multi-purpose tree crop. However, bottleneck in seedling production to fully domesticate this crop has not been resolved. This study was carried out to compare the effect of three different soilless media on the producti...

Open access Research Article 10.9734/IJPSS/2015/12739

Frequency of HCV and HBV Co-infections in HIV Positive Patient in City of Iran: A Cross-Sectional Study

Fatemeh Saleh, Hossein Azizi, Farnaz Kheirandish, Fariborz Rashnou, Seyed Dawood Mousavi Nasab, Fatollah Movahedi & Maryam Azizi · International Journal of TROPICAL DISEASE & Health · 2014

Aims: One of the current crises of the society is prevalence rate of viral co-infection of hepatitis B and C among HIV patients.HIV, HBV, and HCV are major public health concerns. Because of shared routes of transmission, HIV-HCV coinfection and HIV-HBV coinfection are common. HI...

Open access Research Article 10.9734/IJTDH/2015/13282

Effect of Different Sowing Dates on Growth and Yield of Three Pearl Millet (Pennisetum glaucum (L.) R. Br) Cultivars in West Darfur Sudan

M. M. H. Bashir, S. O. Yagoub & S. A. Ahmed Mohammed · International Journal of Plant & Soil Science · 2014

Aim: To study the effect of sowing dates on growth and yield of three pearl millet (Pennisetum glaucum (L.) R. Br) cultivars. Study Design: The treatments were arranged in split plot design with four replicates. Place and Duration of Study: Field experiments were conducted for tw...

Open access Research Article 10.9734/IJPSS/2015/14068

Introduction of New Landrace Varieties Adapted to Drought Stress

Bahram Heidari, Laleh Ghaed-Rahimi & Ali Dadkhodaie · International Journal of Plant & Soil Science · 2014

Screening and introducing landrace varieties (as useful cultigens) is important for cultivation under abiotic stresses in temperate regions with low precipitations. To evaluate the response of wheat (Triticum aestivum L.) landraces to post-heading drought stress, two types of cul...

Open access Research Article 10.9734/IJPSS/2015/14960

Effect of Cow Dung on Soil Properties and Performance of Sweet Potato (Ipomoea batatas L.) in Sudan Savanna, Nigeria

M. Haliru, A. U. Dikko, M. Audu & I. Aliyu · International Journal of Plant & Soil Science · 2014

The study was conducted during the 2011/2012 dry season at two locations simultaneously, to evaluate the effect of cow dung rates on some selected soil chemical properties and performance of sweet potato. The trials were conducted at Usmanu Danfodiyo University, Sokoto vegetable...

Open access Research Article 10.9734/IJPSS/2015/14471

Antioxidant Property and Cardiovascular Effects of Coconut (Cocos nucifera) Water

K. N. Agbafor, S. O. ELOM, M. E. Ogbanshi, A. O. Oko, A. J. Uraku, V. U. O. Nwankwo, K. I. OBIUDU & B. Ale · International Journal of Biochemistry Research & Review · 2014

Coconut water, a natural nutritious beverage that contains several biologically active chemical substances, is used in the management/treatment of several disorders in Eastern Nigeria. This study was set up to evaluate the antioxidant potential of coconut water and its effect on...

Open access Research Article 10.9734/IJBCRR/2015/9805

The E1 Copper Binding Domain of Full-Length Amyloid Precursor Protein Promotes Epithelial to Mesenchymal Transition in DU145 Cells in an Isoform-Specific Manner

Mallory Gough, Craig Delury & Edward Parkin · International Journal of Biochemistry Research & Review · 2014

The E1 Copper Binding Domain of Full-Length Amyloid Precursor Protein Promotes Epithelial to Mesenchymal Transition in DU145 Cells in an Isoform-Specific Manner Epithelial to mesenchymal transition (EMT) confers migratory and dynamic properties on cells and, as such, plays a pivo...

Open access Research Article 10.9734/IJBCRR/2015/14873

Evaluation of the Effects of Methanolic Extract of Alligator Pepper (Aframomum melegueta) on Serum creatinine, Blood Urea Nitrogen and Electrolytes in Wistar Albino Rats

S. O. Onoja, M. I. Ezeja, Y. N. Omeh & J. T. Ekwulu · International Journal of Biochemistry Research & Review · 2014

Evaluation of the Effects of Methanolic Extract of Alligator Pepper (Aframomum melegueta) on Serum creatinine, Blood Urea Nitrogen and Electrolytes in Wistar Albino Rats The effect of methanolic extract of Alligator pepper (Aframomum melegueta) (AME) on the serum creatinine, bloo...

Open access Research Article 10.9734/IJBCRR/2015/15061

Prognostic Value of Leptin Gene Polymorphisms in Type 2 Diabetes Mellitus Patients in Egypt

Mahmoud abdel-Aziz Elrehany, Ahmed Mohamed Okasha, Ahlam Mohamed Abdellah, Hesham Ahmed Abdel-Naby & Ahmed Mokhtar Ahmed Sidky · International Journal of Biochemistry Research & Review · 2014

Prognostic Value of Leptin Gene Polymorphisms in Type 2 Diabetes Mellitus Patients in Egypt Aim: The work wasto study polymorphisms in the LEP gene in type 2 diabetics in Minia, Egypt and determined the relationship between the leptin and c-peptide levels in different genotypes a...

Open access Research Article 10.9734/IJBCRR/2015/14694