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All published articles 118069

Mesenchymal Stem Cell-based Cancer Gene Therapy: Application and Unresolved Problems

Sinh Truong Nguyen, Viet Quoc Pham, Ngoc Kim Phan & Phuc Van Pham · Annual Research & Review in Biology · 2014

There are many barriers that have hindered the progress of clinical application of gene therapy as a potential method for treating cancer. These limitations are caused by transduction/delivery failure rates with viral vector systems and were due to the resultant non-specific targ...

Open access Research Article 10.9734/ARRB/2014/7305

Good Orchard Maintenance and Agronomic Practices as Working Components in Management of Dieback Disease on Passion Fruit (Passiflora sp.) in Kenya

Carolyne W. Wangungu, Maina Mwangi, Ruth Gathu & Reuben Muasya · Annual Research & Review in Biology · 2014

Passion fruit is of high economic importance in Kenya. In the recent past, diseases have led to decline in fruit production. This study aimed at identifying disease management practices that could be adopted to mitigate disease impacts. Passion fruit varieties used include purple...

Open access Research Article 10.9734/ARRB/2014/5092

Differential Spectrophotometric Method for Determination of Cefquinome Sulphate

S. Shantier & E. Gadkariem · Journal of Pharmaceutical Research International · 2014

Differential first derivative (ΔD1) method is developed for the quantitative analysis of cefquinome sulphate (CS) in bulk and dosage form. The method is based on measuring the ΔD1 of CS in alkaline solutions against its neutral aqueous solutions as blanks. The proposed method is...

Open access Research Article 10.9734/BJPR/2014/5734

In vitro Antioxidant Activity of Lectin from Different Endophytic Fungi of Viscum album L.

T. S. Sadananda, M. Govindappa & Y. L. Ramachandra · Journal of Pharmaceutical Research International · 2014

Objective: To evaluate the antioxidant potential of lectin from the endophytic fungi of Viscum album. Place and duration of study: Department of Biotechnology, Shridevi Institute of Engineering and Technology campus, Tumkur, Karnataka, India between November 2012 and March 2013....

Open access Research Article 10.9734/BJPR/2014/6702

In vitro and in vivo Antitrypanosomal Effects of Methanol and Aqueous Extracts of Picralima nitida

A. C. Ene, N. G. Edeh, C. Bonny-Okoli, O. A. Ojiako, C. O. Ujowundu & C. U. Igwe · Journal of Pharmaceutical Research International · 2014

The methanol and aqueous extracts of the leaves, fruits, seeds, stem bark and roots of Picralima nitida were studied in vitro and in vivo for activity against Trypanosoma brucei brucei in Swiss albino mice. Phytochemicals studies were also conducted for all the plant extracts The...

Open access Research Article 10.9734/BJPR/2014/6628

Carcinogen Metabolizing Enzymes: Modulation of Their Activities in Liver, Lung and Stomach by Thymoquinone

Said Al-Dalaen, Samir Mahgoub & Aiman Al-Qtaitat · European Journal of Medicinal Plants · 2014

Background: Thymoquinone (TQ), the bioactive constituent of black seed (Nigella sativa), has been shown to inhibit the growth of various human cancerous cells both in vitro and in vivo. Aim: To characterize the effects of thymoquinone on the activity of phase I and phase II carci...

Open access Research Article 10.9734/EJMP/2014/3870

Germination Eco-physiology of Angelica glauca Edgew Seeds

J. S. Butola, R. K. Vashistha, C. P. Kuniyal, A. R. Malik, Aasif Ali & S. S. Samant · European Journal of Medicinal Plants · 2014

Aims: Angelica glauca Edgew is a heavily exploited critically endangered medicinal cum aromatic herb of Himalayan region. Poor and erratic seed germination is one of the constraints in its in-situ as well as ex-situ conservation and large scale cultivation. Moreover, our understa...

Open access Research Article 10.9734/EJMP/2014/7527

Standardization of Andrographis paniculata, Mitracarpus scaber and Nauclea latifolia Herbal Preparations as per European and Nigerian Drug Regulations

Sunday J. Ameh, Nneka Ibekwe, Aminu Ambi, Obiageri Obodozie, Mujtaba Abubakar, Magaji Garba, Herbert Cocker & Karniyus S. Gamaniel · European Journal of Medicinal Plants · 2014

Background: Herbal drug standardization (HDS) is multidisciplinary with botany and chemistry working together to facilitate decisions on production of herbal medicines. The common reasons for HDS are: i) it creates the need for establishing botanical identity; ii) it is necessary...

Open access Research Article 10.9734/EJMP/2014/5457

Nutritional Assessment and Mineral Composition of Some Selected Edible Vegetables

Najeeb Ur Rehman, Javid Hussain, Liaqat Ali, Abdul Latif Khan, Fazal Mabood, Syed Abdullah Gillani & Ahmed Al-Harrasi · European Journal of Medicinal Plants · 2014

Aims: The present study aimed to assess the nutritional significance of some of the commonly consumed vegetables collected from Hangu, Khyber Pakhtunkhwa, Pakistan. Study Design: The study was designed in randomized block design and each analysis was performed with three replicat...

Open access Research Article 10.9734/EJMP/2014/5271

Anti-ulcerogenic Effects and Anti-oxidative Properties of Ceiba pentandra Leaves on Alloxan-induced Diabetic Rats

C. A. Anosike, J. C.Ugwu, P. C. Ojeli & S. C. Abugu · European Journal of Medicinal Plants · 2014

Aims: To evaluate the protective effects of methanol extract of Ceiba pentandra leaves on indomethacin and ethanol induced gastric ulcer and on oxidative stress indices of alloxan-induced diabetic rats. Study Design: Extraction and administration of graded doses of the extract Pl...

Open access Research Article 10.9734/EJMP/2014/6479

Phytochemical and Anti-microbial Screening of the Leaves and Twigs of Sclerocarpus africanus (Jacq)

R. G. Ayo, J. A. Ndiombueze & T. A. Tor-Anyiin · European Journal of Medicinal Plants · 2014

Aim: To determine phytochemical constituents and antimicrobial activity of leaves and twigs of Sclerocarpus africanus (Jacq);  prove or otherwise  ethno-medicinal claims on S. africanus. Place and Duration of Study: Departments of Chemistry, Biological sciences and  Microbiology,...

Open access Research Article 10.9734/EJMP/2014/7096

Structural Analysis and Docking of Stilbene Synthase Protein from Chinese Grape Vine Vitis pseudoreticulata

K. Divya, G. Venkata Ramana & K. V. Chaitanya · Biotechnology Journal International · 2014

Aims: The present work aims to perform the molecular modeling of stilbene synthase protein from Chinese grape vine Vitis pseudoreticulata. Place and Duration of Study: The study has been performed in the Department of Biotechnology, GITAM Institute of Technology, GITAM University...

Open access Research Article 10.9734/BBJ/2014/3835

Type the Characteristics of Pacemaker (PM) Patients Admitted in Stroke Unit: The Stroke Pacemaker Study (SPACES)

M. Spinelli, G. Silvestrelli, S. Micheli, M. Paciaroni, G. Agnelli, A. Lanari & F. Corea · International Blood Research & Reviews · 2014

Aims: According to recent surveys, despite health care authority’s budget reductions, the total amount of PM implants increased worldwide. Even if the diffusion of these devices is large no data are available concerning the characteristics of PM patients hospitalized for stroke....

Open access Research Article 10.9734/IBRR/2014/5693

Phenotypic and Genotypic Characteristics of Rhizobia Isolated from Meknes-tafilalet Soils and Study of Their Ability to Nodulate Bituminaria bituminosa

Btissam Ben Messaoud, Imane Aboumerieme, Laila Nassiri, Elmostafa El Fahime & Jamal Ibijbijen · Microbiology Research Journal International · 2014

Aims: The objectives were to isolate and characterize phenotypically and genotypically the rhizobial strains from the soils belonging to the Meknes-Tafilalet region in order to select strains that are able to nodulate Bituminaria bituminosa. Study Design: An experimental study. P...

Open access Research Article 10.9734/BMRJ/2014/6172

Salmonella Enteritidis Flagella may Enhance Attachment and Invasion of Hen Ovarian Granulosa Cells and Induce Protective Immune Response in Egg-laying Hens

Anwar Ali Abdulla, Mokhtar Arshad & A. Mahdi Saeed · Microbiology Research Journal International · 2014

Aims: To study the effect of flagellin on bacterial attachment and invasion of avian ovary cells in vitro by comparing the attachment and invasion of wild-type S. Enteritidis with non-motile mutants. To assess the immunogenic properties of extracted flagellin against Salmonella E...

Open access Research Article 10.9734/BMRJ/2014/7425