Contemporary civilization is facing more than thousands of disorders accompanied with free radicals. Antioxidants from edible and non-edible mushrooms are gaining importance to fight these disorders. The current investigation was intended to evaluate antioxidant and cytotoxic eff...
Open access
Research Article10.9734/bjpr/2016/30594
Introduction: Recently there has been a great deal of interest in the health benefits of phytochemicals, particularly prenylated and allylated flavonoids. Chalcones (1, 3-diaryl-2-propen-1-ones) and their derivatives are important intermediates of the flavonoid synthetic pathway....
Open access
Research Article10.9734/bjpr/2016/28243
Acacia mearnsii is characterized as a tree with dark green leaves and grow on any types of soil. Its bipinnate leaves with individual leaflets that are used in folk medicine in wound healing, antioxidant, anti-inflammatory and antiviral. Phytochemical tests demonstrated the prese...
Open access
Research Article10.9734/bjpr/2016/30173
This study was designed to determine the acute and subacute toxicity of non-ionic surfactant, sorbitan monostearate (Span 60) vesicles in a Sprague Dawley rat model. The primary aim was to investigate the acute toxicity of Span 60 niosomes after single intraperitoneal (IP) as wel...
Open access
Research Article10.9734/bjpr/2016/30380
Introduction: The rapid increase in the use and consumption of herbal remedies worldwide has been stimulated by several factors, including the notion that most herbal products are safe and effective. Aim: This work was designed to evaluate the acute and subchronic toxicity of ora...
Open access
Research Article10.9734/bjpr/2016/27237
The Mucoadhesive drug delivery system has occupied an important place in the field of pharmaceutical research. Mucoadhesive tablets prolong the residence time of the drug at the site of application and provide extended therapeutic effect. Mucoadhesive tablets have been prepared f...
Open access
Research Article10.9734/bjpr/2016/30629
Nigella sativa is considered as a miracle drug. Although there is a list of diseases which can be treated by it but role of N.s seeds in treatment of diabetes is substantially important. There are multiple classes of antidiabetic agents which ameliorate the hyperglycemia by diffe...
Open access
Research Article10.9734/bjpr/2016/30684
Aims: This study was aimed to evaluate the potential of using Raphia hookeri gum as a binder in tablet formulations. Study Design: Extract of Raphia hookeri gum was investigated as a binding agent in paracetamol tablet formulation in comparison with gelatin BP as standard binder....
Open access
Research Article10.9734/bjpr/2016/28610
Aims: This paper mentions of the investigation of the enzymes binding to Voglibose and the choice of the enzyme which is suitable for drug enzyme interaction as used in biosensing. Voglibose is an antidiabetic drug which is reactive and hence used in very low concentrations. The...
Open access
Research Article10.9734/bjpr/2016/30369
Aims: This study was undertaken to characterize the bioactive constituents of Apium leptophyllum fruits and to evaluate their cytotoxicity, anti-inflammatory and alpha-amylase inhibitory effects. Study Design: Isolation and identification of the phytochemicals from the petroleum...
Open access
Research Article10.9734/bjpr/2016/30289
Drug delivery to the posterior segment of the eye is a significantly challenging task due to the underlying physiological, anatomical and metabolic constraints. Delivery of drugs through ophthalmic route is significantly hindered by multiple physiological processes including pote...
Open access
Research Article10.9734/bjpr/2016/30601
Aims: A simple TLC Spectrodensitometric method was developed for analysis of Orphenadrine Citrate (OR), Caffeine (CAF) and Aspirin (ASP) either in pure form or in their pharmaceutical preparations. Study Design: Validation study. Methodology: In this method, The three drugs were...
Open access
Research Article10.9734/bjpr/2016/31194
Purpose: To develop a highly selective, reproducible & precise rugged bio analytical method for estimation of Bortezomib (BTZ), “A Protease Inhibitor” in human plasma by validating the developed method in accordance to US-FDA guidelines. Methodology Envisaged: BTZ D3 was used as...
Open access
Research Article10.9734/bjpr/2016/30565
Objective: Lubricants are additives which reduce friction and so essential components of drug formulation. This piece of work was initiated to evaluate coconut oil as a co-processed lubricant in the formulation and compression of paracetamol tablets in comparison with magnesium s...
Open access
Research Article10.9734/bjpr/2016/31379
Ocimum sanctum (L) is a well-known herbal plant used for the treatment of bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases and insect bites. It is proposed to have anticancer, antidiabetic, antifungal, antimicrobial, cardio protective, analgesic and...
Open access
Research Article10.9734/bjpr/2016/31445