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International Research Journal of Gastroenterology and Hepatology

Published by SCIENCEDOMAIN international

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100

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2026 articles

100

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Articles (100)

Prevalence and Risk Factors for Metabolic-dysfunction Associated Fatty Liver Disease in South Indian Population

Dhivya E, Kandasamy Kumar E, Poppy Rejoice, Shafique A & Geetha D · International Research Journal of Gastroenterology and Hepatology · 2024

Background: Metabolic associated fatty liver disease (MAFLD) is a new definition proposed by the global consensus panel in 2020 for liver disease associated with known metabolic dysfunction. Based on new diagnostic criteria, we aimed to investigate its prevalence and risk factors...

Open access Research Article 10.9734/irjgh/2024/v7i1106

Role of Routine Bone Marrow Biopsy Preoperatively in Non Cirrhotic Portal Hypertension

Karthik Chalamalasetti, Sugaprakash Sankareswaran, Prabhakaran Raju & Sugumar Chidambaranathan · International Research Journal of Gastroenterology and Hepatology · 2024

Background: A bone marrow biopsy is routinely done prior to surgical intervention in patients with Extrahepatic portal venous obstruction (EHPVO) and Non-Cirrhotic portal fibrosis (NCPF) to rule out other aetiologies pertaining to pancytopenia. However, there are no guidelines fo...

Open access Research Article 10.9734/irjgh/2024/v7i1105

Complex Interplay of Cardiac, Hepatic, and Renal Dysfunction in a Patient with Extra-hepatic Portal Vein Obstruction and Rheumatic Mitral Stenosis: A Case Report

Jasper Victoria Leelarani Martinraj & Keren Ann George · International Research Journal of Gastroenterology and Hepatology · 2024

This case report presents a 31-year-old male with a complex interplay of cardiac, hepatic, and renal dysfunction, characterized by extra-hepatic portal venous obstruction (EHPVO), decompensated chronic liver disease (DCLD), and rheumatic heart disease (RHD) with severe mitral ste...

Open access Research Article 10.9734/irjgh/2024/v7i1104

Effect of Age on Colonic Damage Induced by Cadmium Exposure in Female Wistar Rats

Serah Funke Ige, Ibukunoluwa Victor Fayemi, Julius Ayomide Ayoola, Mariam Ololade Olasupo, Olajumoke Deborah Ogunleye, Gbenga Opeyemi Owolabi & Taiwo Adebayo Ajagbe · International Research Journal of Gastroenterology and Hepatology · 2024

Background: Cadmium, a known genotoxic metal, has been shown to worsen colonic damage in both animal models and human studies. Research has indicated that cadmium accumulation in the colon results in mucosal damage, inflammation, disrupted immune responses, and an increased risk...

Open access Research Article

Seroprevalence of Helicobacter pylori Infection among Adults in Port Harcourt Metropolis, Nigeria

Chidi L.C. Ndukwu, Owhorchukwu Amadi-Wali & Roseanne Adah Ikpeama · International Research Journal of Gastroenterology and Hepatology · 2024

Introduction: Helicobacter pylori is a highly evolved and adapted pathogen, notorious for having infected half of all the people in the world. It is linked as a causative agent for numerous benign and malignant diseases of the digestive tract, such as peptic ulcer disease (PUD) a...

Open access Research Article

Oxidative Stress Markers in Malaria Patients: Assessing the Impact of Parasitaemia Severity at Rivers State University Teaching Hospital, Nigeria

Odum, J., Obisike, U.A. & Elekima, I. · International Research Journal of Gastroenterology and Hepatology · 2024

Aim: The present study aimed to assess the levels of some oxidative stress markers in malaria parasite-infected subjects attending Rivers State University Teaching Hospital, Port Harcourt, Nigeria. Background: Malaria can be fatal, the severity of malaria infection is closely lin...

Open access Research Article

Resmetirom in the Treatment of Noncirrhotic Non-Alcoholic Steatohepatitis: An In-Depth Review

Parita Chorghe, Priyanka Das, Aanchal Gvalani, Sunaina Anand & Anish Desai · International Research Journal of Gastroenterology and Hepatology · 2024

Background: Non-alcoholic steatohepatitis (NASH) is emerging as a significant global health challenge, closely linked to obesity and metabolic disorders. Despite its increasing prevalence, effective pharmacotherapy remains limited. Resmetirom, a selective thyroid hormone receptor...

Open access Research Article

Expert Perspectives on the Prescription Practice of Esomeprazole Alone or in Combination with Domperidone for Acid Peptic Disease Management in Indian Settings

Manjula S & Krishna Kumar M · International Research Journal of Gastroenterology and Hepatology · 2024

Objective: To gather expert perspectives on the use of esomeprazole monotherapy or its combination with domperidone for managing acid-peptic disease (APD) in routine Indian settings. Methods: This cross-sectional study employed a 24-item questionnaire to gather expert opinions on...

Open access Research Article

Biochemical Effects of High Concentration of Colocasia Esculenta Flour Fed on Streptozotocin-Induced Diabetic Rats

Uro-Chukwu, H.C, Ezekwe, A.S, Roberts, F, Okari, K. A & Uro-Chukwu, F.N.C · International Research Journal of Gastroenterology and Hepatology · 2024

Background: An endocrine and metabolic disease of the pancreas such as Diabetes Mellitus (DM), is of Public health dimension responsible for 536.6 million cases in the globe. The treatment of DM takes lots of resources, making alternative treatment options like the utilization of...

Open access Research Article

Impact of Palm Oil Tainted Feed on Liver and Kidney Health in Wistar Rats: A Sub Chronic Study

Kanayo Mercy Odia & M. Aniyeloye · International Research Journal of Gastroenterology and Hepatology · 2024

Background: Palm oil is an edible vegetable oil obtained from the mesocarp (reddish pulp) of the fruit of the oil palm trees. The present study evaluated the effects of sub-chronic consumption of palm oil-tainted feed (POTF) on hepatorenal parameters in male Wistar rats. Methods:...

Open access Research Article