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International Research Journal of Gastroenterology and Hepatology

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100

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2026 articles

100

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Articles (100)

Complete Response to Pembrolizumab in a Patient with Lynch Syndrome: A Case Report

Aref Chelal & Ashraf ALakkad · International Research Journal of Gastroenterology and Hepatology · 2022

Background: Lynch syndrome LS is a life-threatening condition caused by heterozygous mutations in mismatch repair genes (MMR). People with this syndrome are at increased risk of developing different types of cancers, such as colorectal carcinomas, endometrial cancer, and ovarian...

Open access Research Article

Liver Fibrosis in a Healthy Population in Jos, North-central Nigeria

David Nyam P., Duguru Mary J., Davwar Pantong M., Makpu Jireh D., McHenry Stephen I., Ogwuche John E., Okwute Atta, Obekpa Solomon, Kenis Shedrack F., Kajo Jesse I. & Okeke Edith N. · International Research Journal of Gastroenterology and Hepatology · 2022

Introduction: The excessive accumulation of extracellular matrix protein, primarily collagen, leads to the fibrosis of the liver, and when fibrosis becomes advanced, it leads to liver cirrhosis. Liver cirrhosis is progressive hepatic fibrosis characterized by distortion of the li...

Open access Research Article

Evaluation of the Hepatotoxic Potential of Methanol Leaf Extract of Menta piperitha Using Animal Model

C. D. Ubani, A. K. Amah, C. C. Ofoegbu & D. C. Ejiofor · International Research Journal of Gastroenterology and Hepatology · 2022

The aim of this research work was to evaluate the hepatotoxic potential of methanol leaf extract of M. piperita. Freshly harvested leaf of M. piperita was dried at room temperature and afterwards ground to fine powder. 500 g of powdered plant sample was soaked in 70% methanol for...

Open access Research Article

Factors Associated with Gastritis in Adolescents Aged 10 to 17 Years at Matanda Hospital in the Democratic Republic of Congo

Maliyabwana Themomwinda Josué, Dimoke Okito Franck, Diessa Nyongombe Eric & Assani Ramazani Raymond · International Research Journal of Gastroenterology and Hepatology · 2022

This study, conducted at Matanda Hospital from 1 January to 31 September 2021, focused on the factors associated with gastritis in adolescents aged 10 to 17 years, with a view to contributing to the promotion and improvement of adolescents's health. The objectives of the study we...

Open access Research Article

Evaluation of the Effect of Ethanolic Extract of Solanum torvum Leaf on Liver of Treated Rats

Nweke Elizabeth Obioma & Nwizu, Olive Ogechi · International Research Journal of Gastroenterology and Hepatology · 2022

The aim of this study was to evaluate the effect of ethanolic extract of Solanum torvum leaf on the liver of treated Wistar rats. Freshly harvested leaves of S.torvum were shade dried and ground to fine powder. 500 g of powdered plant sample was macerated in ethanol for 72 hrs. T...

Open access Research Article

Medullary Carcinoma of the Colon : A Case Study

A. Zouhair, A. Moufakkir, R. Boufettal, A. Hajri, D. Erguibi, SR. El Jai & F. Chehab · International Research Journal of Gastroenterology and Hepatology · 2022

Medullary adenocarcinoma (MC) is a variant of colonic cancer,and it has morphological similarity to poorly differentiated adenocarcinomas. MC has been categorized as a rare variant of colorectal adenocarcinoma with leaves of malignant cells with vesicular nuclei, prominent nucleo...

Open access Research Article

Colorectal Cancer Screening: Insights from A Prospective National Survey of Patients and Healthcare Providers

David A. Johnson, Katie S. Lucero, John Maeglin, Shari Dermer & Douglas K. Rex · International Research Journal of Gastroenterology and Hepatology · 2022

Offering screening for colorectal cancer (CRC) to all age-appropriate and medically suitable patients is the standard of medical care in the United States. Provider advice is important for patients to accept screening for CRC. Previous research suggests that physicians’ self-dire...

Open access Research Article

Assessment of the Effects of Some Herbal Supplements on Some Inflammatory and Hepatic Markers of Cyanide– Induced Hyperthyroid Female Albino Rats

E. O. Nwachuku, B. N. C. Onuoha, D. G. Tamuno-Emine & I. Elekima · International Research Journal of Gastroenterology and Hepatology · 2022

Aim: To assess the effects of some herbal supplements on some inflammatory and hepatic markers of cyanide – induced hyperthyroid female Albino Rats. Study Design:  Experimental study. Place and Duration of Study: Department of Animal and Environmental Sciences, Rivers State Unive...

Open access Research Article

Hepatoprotective Potentials of Ethanolic Leaf-Extract of Cajanus cajan (linn) in Ethanol-evoked Oxidative Stress in Albino Rats

Celestine O. Ogbu, Inalegwu Bawa, Suleiman Zakari, Ocheleka M. Itodo, Hajara Zakari, Ameh Maltilda & Christian E. Offor · International Research Journal of Gastroenterology and Hepatology · 2022

Aims: The hepatoprotective potentials of ethanolic leaf-extract of Cajanus cajan (linn) in ethanol-evoked oxidative stress was examined by checking the activities of liver function parameters such as Alanine Transaminase (ALT), Aspartate Transaminase (AST) and Alkaline Phosphatas...

Open access Research Article

Gastrointestinal Stromal Tumor (GIST): Case Study

Anwar Kamel Adwan, Ashraf ALakkad, Fadi Bassam Almahameed & Maher Fahd Hejazee · International Research Journal of Gastroenterology and Hepatology · 2022

A 38-year-old male presented with a complaint of upper GIT bleeding. The patient is an alcoholic and a smoker for the last 5 years. The patient had vomited blood for the last three days. Endoscopy, Biopsy, Esophagogastroduodenoscopy and CT scan of abdomen and pelvis with IV contr...

Open access Research Article