Prevalence and Hospitalizations of Cardiovascular Disease Complications in Adults with Diabetes: A Comprehensive USDDS Database Analysis

Abstract

Background: Cardiovascular disease (CVD) is a significant cause of morbidity and mortality among adults with diabetes. Understanding the prevalence and trends in hospitalizations for CVD complications in this population is crucial for informing healthcare strategies and interventions. Aim: This study aimed to analyze the prevalence and hospitalization rates of CVD complications among adults with diabetes using data from the USDSS database. Methods: This retrospective study analyzed USDSS database data from 2000 to 2020, exploring CVD complications' prevalence and hospitalization patterns in adults with diabetes.The study explored prevalence rates of major CVD complications, including heart disease and stroke, alongside demographic factors like age, gender, race/ethnicity, and education level. Hospitalization rates for ischemic heart disease, heart failure, and stroke were calculated. Temporal trends were analyzed graphically, and statistical tests (chi-square, ANOVA) with a significance level of p<0.05 were conducted. Results: The analysis revealed notable temporal trends in major heart disease prevalence and stroke rates among adults with diabetes. Over the study period, major heart disease incidence increased from 2.7 in 2000 to 4.9 in 2022, with an average of 4.22. Prevalence ranged from its lowest at 18.2% in 2014 to its highest at 23.7% in 2001, with the latest at 17.4% in 2022. Stroke cases rose steadily from 1.1 in 2000 to 2.1 in 2022, with the latest prevalence at 7.4%. Subgroup analysis revealed variations across gender, age, race, and education levels. Hospitalization rates for CVD declined from 78.6 per 1,000 in 2000 to 46 per 1,000 in 2020. Rates for ischemic heart disease decreased from 32.2 per 1,000 to 10.2 per 1,000, heart failure from 20.7 per 1,000 to 15 per 1,000, and stroke from 9.4 per 1,000 to 8.4 per 1,000. Conclusion: This study provides valuable insights into the prevalence and hospitalization trends of cardiovascular disease complications among adults with diabetes in the United States. The findings underscore the importance of targeted interventions to reduce the burden of CVD in this population.