Antioxidant Activity of Polyphenolic Leaf Extract from Santolina chamaecyparissus L. (Asteraceae) and the Isolated Luteolin-7-O-Glucoside
Chahra Boudoukha, Hamama Bouriche, Mahfuz Elmastas, Huseyin Aksit, Omer Kayir, Nusret Genc, Abderrahmane Senator
Journal of Pharmaceutical Research International · pp. 1–12 · Published 8 May 2018
10.9734/JPRI/2018/40726Abstract
Aim: The present study aimed to investigate the chemical constituents and antioxidant potential of Santolina chamaecyparissus polyphenolic extract (SCPE). Materials and Methods: The extract containing phenolic compounds, was extracted with ethyl acetate and luteolin-7-O-glucoside was separated and purified using flash chromatography on silica gel column. This isolated compound was identified according to its physicochemical properties and spectral data (UV, LC–TOF-MS, 1H NMR, 13C NMR and 2D NMR). In vitro antioxidant activity of the isolated compound and SCPE was investigated using DPPH•, ABTS+, reducing power, superoxide anion radical scavenging and β-carotene bleaching assays. Results: Results showed that SCPE and luteolin-7-O-glucoside exhibited significant antioxidant activity. The antioxidant activity of SCPE was comparable to that of luteolin-7-O-glucoside. Luteolin-7-O-glucoside was isolated for the first time from Santolina chamaecyparissus polyphenolic extract. Conclusion: Results of the present investigation clearly indicate that SCPE and isolated compound (luteolin-7-O-glucoside) have powerful antioxidant capacity against various antioxidant systems in vitro
Cited by 8
A. V. Myagchilov, A. I. Kalinin · Chemistry of Natural Compounds · 2024
Charaf Eddine Watheq Malti, Clémentine Baccati, Magali Mariani · Molecules · 2019
Adem Necip, İbrahim Demirtaş · 2025
J.A. Cortes-Morales, A. Olmedo-Juárez, M. González-Cortazar · Experimental Parasitology · 2022
Loubna Ait Dra, Maria João Rodrigues, Nuno da Rosa Neng · Industrial Crops and Products · 2019
Jorge M. Alves-Silva, Sónia Pedreiro, Mónica Zuzarte · Plants · 2024
Yuan Ma, Ailian Meng, Ping Liu · Molecules · 2022
Qizhong Cai, Changzheng Liu, Lu Liu · Frontiers in Plant Science · 2022
Related research
- In vitro Antioxidant and Anticancer Activity of Cyanobacteria — shares topic coverage
- Review: Parkia speciosa as Valuable, Miracle of Nature — shares topic coverage
- A Selective Review of Lipid Autoxidation and Rancidity, Antioxidants, and Dithiooxamide — shares topic coverage
- Antioxidant and Haemato-Biochemical Enhancing Properties of Daucus carota in Male Wistar Rats Toxicated with Lead Chloride — shares topic coverage
- Radical Scavenging Capacity and Efficacy of Myristica fragrans (Nutmeg) Metabolites on Cladosporum herbarum of Food Origin — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
8
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.