Study of Antibiotic Sensitivity of Pseudomonas aeruginosa Isolated from Women with Urinary Tract Infection

Abstract

UTIs, or urinary tract infections, are among the most prevalent infections in the world. It is estimated that 7% to 10% of UTIs are caused by Pseudomonas aeruginosa. Antibiotic resistance levels in P. aeruginosa isolates from UTIs are often greater than in E. coli isolates. So, the current study aimed to test the antibiotic sensitivity to P. aeruginosa isolated from patients with urinary tract infection. Clinical samples (95) were collected from Kirkuk Hospital in Kirkuk city for the period from May to August 2024 from women who were admitted and hospitalized after consulting the specialist doctor and referring him to the laboratory. The method of collecting samples included the following: Urine samples were taken from women with UTI ranging in age from (5-59 years) of women, after which they were transferred directly to the laboratory to be cultured on the culture media. Of the total samples investigated, 64 (or 67.4%) showed positive findings for P. aeruginosa growth when cultured on the blood agar, cetrimide agar, and MacConkey agar. The isolation rate of P. aeruginosa from women with urinary tract infection was 18.8%. For antibiotic susceptibility test, P. aeruginosa showed 81.8%, 93.8% and 94.9% sensitive toward Gentamycin, Imipenem and Amikacin. On the other hand, P. aeruginosa was completely sensitive (100%) toward Tobramycin. Its concluded that P. aeruginosa is one of the main causes of urinary tract infection in women.