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Research Article Open access CC BY 4.0

Evaluation of Empirical Functions and Fate of Isomaltose

Toluwase Hezekiah Fatoki, David Morakinyo Sanni, Daniel Uwaremhevho Momodu, Harriet Unuagbon Ugboko, Catherine Joke Adeseko, Bolanle Christianah Faleye

Journal of Applied Life Sciences International · pp. 1–10 · Published 9 Feb 2018

10.9734/JALSI/2018/39370

Abstract

Aim: To validate the empirical functions of isomaltose and proposed its fates in metabolism using computational analysis. Place and Duration of Study: This work was carried out at the Department of Biochemistry at the Federal University of Technology Akure Nigeria in 2017. Methodology: We make use of text mining of experimental articles on isomaltose, predicted the potential targets using Swisstargetprediction server, and the Swisssimilarity server was used for drug similarity analysis. Results: Isomaltose exhibits antimicrobial activity, biodegradability, non-toxic, and find its use in food, biochemistry and pharmaceutical industries as a prebiotic molecule, precursor metabolite and potent medicine respectively. Isomaltose possibly has a lower glycemic index, with the fate that implicated the production of diglucosamine, by the help of specific aminotransferase, and that there is a possibility of biosynthesis of secondary metabolites through isomaltose pathway. Conclusion: This study provides the future areas of research and application of isomaltose.  

Isomaltose diglucosamine novel pathway in silico functions fate

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