Study of the Effects of Sorghum bicolor (Poaceae) on Duodenal Motility in Rabbits
KAMBOU Sansan Philippe, Angbo Kousso Marie Angéline, Kolia Kouamé Innocent, Bahi Calixte, Bedou Kouassi Denis, Cissé-Camara Massara
Annual Research & Review in Biology · pp. 23–32 · Published 29 Sep 2025
10.9734/arrb/2025/v40i102317Abstract
In this study,carried out to evaluate the gastrointestinal tolerance of the aqueous extract of Sorghum bicolor leaf sheath used in the treatment of anemia in Côte d'Ivoire. An aqueous extract of whole Sorghum bicolor seeds was prepared using cold maceration method. Segments of rabbit duodenum were used for the experiment. Aqueous extracts of Sorghum bicolor induce a dose-dependent reduction in duodenal muscle contractions. Aqueous extracts of Sorghum bicolor inhibit acetylcholine-induced tonic concentrations by 94% at a concentration of 1000 µg/mL. The aqueous extract of Sorghum. bicolor had intestinal muscle relaxant properties. These results support its pharmacological potential as an antispasmodic agent.
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