Comparative Study of Antibacterial Effects of Curcuma longa Linn. and Zingiber officinale Rosc. Rhizomes
Lucky Abdul Ajige, Tunde Oladipo Sunday, Folasade Abosede Elkanah, Adebimpe Ajiteru Awe, Saheed Abiodun Ayoola, Rita Maneju Sunday
Microbiology Research Journal International · pp. 1–8 · Published 27 Feb 2017
10.9734/MRJI/2017/31551Abstract
Aims: To investigate and compare the antibacterial effect of Curcuma longa with Zingiber officinale rhizome ethanolic extracts against five bacterial species which include three gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis) and two gram-positive bacteria (Staphylococcus aureus andStreptococcus pyogenes). Study Design: Activity directed antibacterial effect of C. longa and Z. officinale using in vitro methods. Place and Duration of Study: Medicinal Plants Section, Bioresources Development Centre, Ogbomoso, Nigeria between March and September, 2016. Methodology: The ethanolic extract was prepared by separately weighing 20, 40 and 60 g of powdered C. longa and Z. officinale into 100 mL of absolute ethanol. The antibiotic sensitivity test was carried out using a sensitivity disc impregnated with various antibiotics including Augmentin (AUG), Ampicillin (AMP), Ciprofloxacin (CIP), Ceptriaxome (CEP) and Ofloxacin (OFL). Results: 40 and 60 g of C. longa and Z. officinale extracts significantly (P < 0.05) inhibited all the isolates (more effect was on S. pyogenes, S. aureus, E. coli, P. mirabilis followed by K. pneumoniae) when compared with 20 g. Also, 40 g of Z. officinale extract significantly (P< 0.05) inhibited the growth of S. pyogenes when compared with C. longa while 60 g of C. longa significantly (P < 0.05) inhibited the growth of P. mirabilis andK. pneumonia when compared with Z. officinale. The minimum inhibitory concentration of both extracts that inhibited E. coli and P. mirabilis was 1.3 g. CIP followed by CEP and OFL were active on all the bacteria used for this study. AUG was slightly active only on K. pneumonia while AMP was not active on any of the test organisms. Conclusion: The result of this study showed that all the gram-positive bacteria used in this study were more sensitive to both C. longa and Z. officinale rhizomes ethanolic extracts as compared to the gram-negative bacteria.
Cited by 1
S Kumar, Akhilesh Kumar, Naveen Kumar · Veterinary research communications · 2022
Related research
- Antimicrobial Assessment of Annona muricata Fruits and Its Chemical Compositions — shares topic coverage
- Plasmid Profile of Multidrug Resistant Bacteria Isolated from Wound Swabs from Hospital Patients in Akure, Nigeria — shares topic coverage
- Molecular Detection of Extended Spectrum Beta-lactamase Resistance in Escherichia coli from Poultry Droppings in Keffi, Nigeria — shares topic coverage
- Microbiological Enumeration of Pathogens Associated with Urinary Tract Infection: Current Scenario and Its Medical Relevance — shares topic coverage
- Synergizing Bacteriophage Therapy and Computational Neuroscience: A Ray of Hope in the Fight against Antibiotic Resistance — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
1
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.