A Study of Chemical Composition and Bioactivity of Folk Medicinal Plant (Teucrium polium)

Abstract

Introduction: Investigating the chemical composition and bioactivity of Teucrium polium, sometimes referred to as Germander, was the goal of the current study. Analysis was done on the T. polium extracts. Numerous chemical components found in it contribute to its therapeutic qualities. Flavonoids, terpenoids, essential oils, and other substances with antioxidant and anti-inflammatory qualities are among these chemicals. Material and Methods: Collected a sample of the leaves and bark of the Teucrium polium plant from the vicinity of the University of Tabuk and produced an extract for analysis. Gas chromatography was used to evaluate the extracts, and Teucrium polium extract's antibacterial qualities were also examined. Results: The ethanol extract outperformed the hexane extract in terms of activity or in other words Hexane extract was less active than ethanolic extract on all other microorganisms.  The hexane extract exhibited a 23 mm inhibitory zone and high antibacterial activity against Escherichia coli. Despite this, the extracts' zones of inhibition for Pseudomonas aeruginosa and Escherichia coli were comparable in size (23, 24, and 23 mm, respectively). Conclusion and Work's Significance: The clinical, pharmacological, and research in medicine sectors, along with the food as well as cosmetics industries, can all benefit from the substantial biological activity of T. polium extracts. They possess a vast array of therapeutic applications and have long been used to cure a range of ailments.