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Research Article Open access CC BY 4.0

Transient Anti PM-Scl75 Antibody Positive Acral Ischemia Syndrome in a 15 Years-Old Girl

Stefan Bittmann, Elisabeth Luchter, Elena Moschüring-Alieva

Asian Journal of Pediatric Research · pp. 37–43 · Published 13 Mar 2024

10.9734/ajpr/2024/v14i3332

Abstract

In 1862, the French doctor Maurice Raynaud published his dissertation in Paris titled "Sur l’asphyxie locale et la gangrène symétrique des extrémités" (On local asphyxia and symmetrical gangrene of the extremities). In it, he described a series of cases in which there were episodes of acral ischemia. The phenomenon later named after him typically involves changes in skin color from white to blue-livid to red, caused by a vasospasm of acral arteries (white phase) followed by reactive vasodilation. Acral ischemia is present in different clinical conditions as stated in this manuscript. We report a case of a transient anti PM-Scl75 antibody positive acral ischemia syndrome in a 15 years-old girl.

Thrombosis embolism blockage oxygen deprivation ischemia

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