Use of Levosimendan in Patients With Low Left Ventricular Ejection Fraction in Ordu/Turkey: Report of Experience with Mini Review

Abstract

Aims:To report the effect of prophylactic usage of levosimendan in patients with low left ventricular ejection fraction undergoing coronary artery bypass grafting (CABG). Methods: We reported early results of 32 patients (26 male and 6 female; mean age 61.630 ± 9.653 years) who  received preoperative levosimendan who underwent CABG with left ventricular ejection fraction (LVEF) of 35% or less between March 2014 and August 2016. Results: All patients achieved to wean from cardiopulmonary bypass. In only four patients there was a need for intraaortic baloon pump (12.5%). Mortality was in 4 patients (12.5%). And six months after the operation all patients (discharged from hospital) were alive. Conclusion: Preoperatively administration of the long-acting inotrope levosimendan might be feasible and have a favourable safety profile in patients with severely reduced LVEF undergoing CABG. We suggest that levosimendan may be useful in high-risk CABG patients.