The Story of Beta-sitosterol- A Review
Soodabeh Saeidnia, Azadeh Manayi, Ahmad R. Gohari, Mohammad Abdollahi
European Journal of Medicinal Plants · pp. 590–609 · Published 7 Feb 2014
10.9734/EJMP/2014/7764Abstract
Aims: Phytosterols are a subgroup of the steroids, as an important class of bioorganic molecules, widespread in plants, animals, marines as well as fungi and have similarity to cholesterol in structure. These compounds have a long history of consumption as food or pharmaceutical products, and generally recognized as safe without undesirable side effects. Place and Duration of Study: Medicinal plants Research Center and Pharmaceutical Sciences Research Center, between March 2013 and May 2013. Results: Amongphytosterols, β-sitosterol is usually used for heart disease, hypercholesterolemia, modulating the immune system, prevention of cancer, as well as for rheumatoid arthritis, tuberculosis, cervical cancer, hair loss and benign prostatic hyperplasia. Furthermore, diverse biological activities whereby natural compounds or the extracts were considered including trypanocidal and mosquito larvicidal, even neutralization of viper and cobra venom characteristics was recorded. Conclusion: Some of the above indications are evidence based, but others are still in doubt and need more investigations to confirm its efficacy and safety. Regarding to the importance of these natural sterols and β-sitosterol as the most abundant of them, the main pharmacological and biological activities together with their clinical trials is reviewed here.
Cited by 269
Ikram Khémiri, Badiaa Essghaier Hédi, Najla Sadfi Zouaoui · Evidence-Based Complementary and Alternative Medicine · 2019
Yudi Purnomo, Juliah Makdasari, Faiqoh Inayah Fatahillah · Journal of Basic and Clinical Physiology and Pharmacology · 2021
Rahmayanti, Ahyar Ahmad · AIP Conference Proceedings · 2020
Christiana A. Kendeson, Mary L. Kagoro, Esther A. Adelakun · Tropical Journal of Phytochemistry and Pharmaceutical Sciences · 2025
Hind Abd-alluh Abu-Hiamed · Pakistan Journal of Nutrition · 2017
Agnieszka Kicel, Joanna Kolodziejczyk-Czepas, Aleksandra Owczarek · Oxidative Medicine and Cellular Longevity · 2018
Diana C. G. A. Pinto, Naima Rahmouni, Noureddine Beghidja · Medicines · 2018
Serap YEŞİLKIR BAYDAR, Rabia CAKİR-KOC, Yasemin BUDAMA KİLİNC · Kocaeli Journal of Science and Engineering · 2021
Andreia S.P. Pereira, Helena den Haan, Jorge Peña-García · Molecules · 2019
Theresa F. Campbell, Joette McKenzie, JeAnn Murray · Journal of Functional Foods · 2017
Showing 114 of 269 known citations — external sources report more than can currently be individually listed.
Related research
- Production of Volatile Compounds by Lactococcus lactis sp. Strain at Different Growth Phases — shares topic coverage
- Triterpenes and Triterpenoids Clinically Useful with Multiple Targets in Cancer, Malaria and More Treatment: Focus on Potential Therapeutic Value — shares topic coverage
- Therapeutics Activities of Amazonian Plant Himatanthus sucuuba (Spruce ex Müll. Arg.) Woodson (Apocynaceae): A Review — shares topic coverage
- Synthesis and Characterization of Se-doped ZnO Nanoparticles by Electrochemical Method: Photodegradation Kinetics of Indigo Carmine Dye and Study of Antimicrobial, Antimitotic Activities of Se-doped ZnO Nanoparticles — shares topic coverage
- Synthesis, Biological Activity and Applications of 1,2,5-Oxadiazol: A Brief Review — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
269
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.