GC-MS Analysis of Phytocomponents and Antifungal Activities of Zanthoxylum acanthopodium DC. Collected from Manipur, India
Okram Zenita Devi, Kottapali Sreenivasa Rao, Ankita Bidalia, Radhapiyari Wangkheirakpam, Okram Mukherjee Singh
European Journal of Medicinal Plants · pp. 1–9 · Published 4 Aug 2015
10.9734/EJMP/2015/19353Abstract
Aims: The aim of this study was to evaluate the antifungal activity and phytochemical analysis of Zanthoxylum acanthopodium to validate the folklore use of this plant. Study Design: The present study was designed to evaluate the antifungal activity in different crude extracts of the Z. acanthopodium leaves followed by the characterization of chemical constituents in the extract which possess highest antifungal activity by using gas chromatography-mass spectrometry (GC-MS). Place and Duration of Study: Department of Botany, University of Delhi and Institute of Bioresources of Sustainable Development, Takyelpat Institutional Area, Imphal between December 2013 and May 2014. Methodology: The antifungal activity of Z. acanthopodium leaf extracts in three organic solvents viz. petroleum ether, ethyl acetate and chloroform were investigated against 5 strains of fungi- Aspergillus flavus, A. fumigates, A. niger, Candida albicans and C. krusei by following agar well diffusion method. The characterization of bioactive compounds in petroleum ether extract was performed using GC-MS by electron ionization in scan mode. Results: The extracts exhibited antifungal activity on two fungal species, namely C. albicans and C. krusei and the petroleum ether extract proved to possess high antifungal activity compared to the rest of the solvent extracts. The GC-MS analysis of petroleum ether extract of Z. acanthopodium leaves identified forty three compounds. Conclusion: GC-MS study highlights the existence of various bioactive compounds in Z. acanthopodium. Paulownin is found as the major compound having highest peak area and it is reported to possess antifungal property which proves that petroleum ether crude extract of Z. acanthopodium could be used as a natural antifungal.
Cited by 13
Trinh Thi Diep, Luong Van Dung, Phung Van Trung · Chemistry & Biodiversity · 2023
Vidia Afina Nuraini · Jurnal Kartika Kimia · 2024
Saumya Agnihotri, Preeti Dobhal, Sumit Mishra · Plant Cell, Tissue and Organ Culture (PCTOC) · 2025
Ravindra H. Patil, Mohini P. Patil, Vijay L. Maheshwari · Apocynaceae Plants · 2023
Yanti, Celinia Harijono, Bibiana Widiyati Lay · Pharmaceuticals · 2023
Adrian, Rony Abdi Syahputra, Nur Aira Juwita · Heliyon · 2023
Ranjana, Zulfa Nooreen, Umme Bushra · Journal of Ethnopharmacology · 2019
C Nilda, Y Abubakar, A Anhar · IOP Conference Series: Earth and Environmental Science · 2025
Yati Nurlaeni, Johan Iskandar, Decky Indrawan Junaedi · Biodiversitas Journal of Biological Diversity · 2021
Shiyang Zhou, Gangliang Huang · Chemistry & Biodiversity · 2023
Related research
- Chemical Constituents Analysis of Petroleum Ether Extract from Xylaria striata by GC-MS — shares topic coverage
- Characterization of Sesquiterpenes and Antibacterial Activities of Extracts from Piliostigma reticulatum (DL.) Hochst and Cleistopholis patens (Benth.) Engl & Diels against Shigella dysenteriae and Streptococcus pyogenes — shares topic coverage
- Evaluation of Secondary Metabolites Profiling of Ginger (Zingiber officinale Roscoe) Rhizome using GC-MS and Its Antibacterial Potential on Staphylococcus aureus and Escherichia coli — shares topic coverage
- Development and Validation of a Paper-Based Strip for Detecting Oil Degradation and Trans-Fat Formation in Repeatedly Heated Palm Oil — shares topic coverage
- Phytochemical Analysis, Antimicrobial and Antioxidant Activity of Clitoria ternatea Blue and White Flowered Leaves — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
13
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.